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AUTOMATIC SCORING OF LUNG DAMAGE

Development of an automatic computed tomography (CT) score to quantify pulmonary involvement in patients with cystic fibrosis.

Cystic fibrosis is the most common inherited genetic disease in the Caucasian population (1/4500). Respiratory involvement is one of the main causes of death. Patients are monitored using clinical and functional markers and chest scans. But these follow-ups take a long time and are too variable. The method developed allows automatic scoring of pulmonary involvement in cystic fibrosis by CT scan. This score is well correlated with respiratory function, which was verified in two independent cohorts of patients.

 

Applications

  • Use in clinical practice for scoring chest scanners
  • Use as a morphological marker in clinical studies
  • Application to other chronic pulmonary diseases with similar CT manifestations

 

Competitive advantages

  • Automatic
  • Quickness of execution
  • Reproductibililty

 

Intellectual property

  • B249382FR D36062

 

Keywords

CT quantification - Automatic scoring - Cystic fibrosis Lung segmentation - Histogram analysis

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